79 achievements for 1520 Gamerscore
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Magdalene
Have 7 or more max red hearts at one time.
15 Gamerscore
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Cain
Hold 55 or more pennies at one time.
15 Gamerscore
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Judas
Kill Satan
15 Gamerscore
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The Womb
Kill Mom.
20 Gamerscore
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Samson
Beat 2 levels in a row without taking damage.
15 Gamerscore
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Eve
Beat 2 levels in a row without picking up any hearts.
15 Gamerscore
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Lazarus
Have 4 or more soul hearts at one time
15 Gamerscore
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Transcendence
Kill Mom's Heart 3 times.
15 Gamerscore
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The Lost
Finish the game's final secret.
20 Gamerscore
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A Quarter
Kill Mom's Heart 8 times.
15 Gamerscore
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Isaac's Tears
Kill Isaac with Isaac.
15 Gamerscore
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Mom's Knife
Kill Satan with Isaac.
15 Gamerscore
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Isaac's Heart
Kill Isaac with The Lost.
15 Gamerscore
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The Mind
Kill Satan with The Lost.
15 Gamerscore
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The Relic
Kill Isaac with Maggy.
15 Gamerscore
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Guardian Angel
Kill Satan with Maggy.
15 Gamerscore
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The Coin Bag
Kill Isaac with Cain.
15 Gamerscore
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The Bomb Bag
Kill Satan with Cain.
15 Gamerscore
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The Guillotine
Kill Isaac with Judas.
15 Gamerscore
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Judas' Tongue
Kill Satan with Judas.
15 Gamerscore
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Eve's Bird Foot
Kill Isaac with Eve.
15 Gamerscore
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The Razor
Kill Satan with Eve.
15 Gamerscore
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Bloody Lust
Kill Isaac with Samson.
15 Gamerscore
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Blood Rights
Kill Satan with Samson.
15 Gamerscore
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Azazel
Make 3 deals with the devil in one run.
15 Gamerscore
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The Satanic Bible
Kill Isaac with Azazel.
15 Gamerscore
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Daemon's Tail
Kill Satan with Azazel.
15 Gamerscore
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Lazarus' Rags
Kill Isaac with Lazarus.
15 Gamerscore
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Broken Ankh
Kill Satan with Lazarus.
15 Gamerscore
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Eden
Beat the Womb for the first time,
15 Gamerscore
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A Blank Card
Kill Isaac with Eden.
15 Gamerscore
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The Book of Secrets
Kill Satan with Eden.
15 Gamerscore
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Something from the Future
Beat the Basement 40 times.
15 Gamerscore
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Something Cute
Beat the Caves 30 times.
15 Gamerscore
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Something Sticky
Beat the Depths 20 times.
15 Gamerscore
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Basement Boy
Beat the Basement/Cellar without taking damage.
20 Gamerscore
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Spelunker Boy
Beat the Caves/Catacombs without taking damage.
20 Gamerscore
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Dark Boy
Beat the Depths/Necropolis without taking damage.
20 Gamerscore
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Mama's Boy
Beat the Womb/Utero without taking damage.
20 Gamerscore
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Dead Boy
Beat the Chest or Dark Room without taking damage.
20 Gamerscore
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Challenges
Beat all 20 Challenges.
20 Gamerscore
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Boss Rush
Beat the Boss Rush.
20 Gamerscore
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Dark Room
Beat the Dark Room.
15 Gamerscore
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The Chest
Beat the Chest.
15 Gamerscore
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Lost Poster
Beat the Dark Room with Isaac.
15 Gamerscore
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Little Baggy
Collect 2 of either Roid Rage, The Virus, Growth Hormones, Experimental Treatment, or Speed Ball.
15 Gamerscore
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The Halo
Kill Mom using the Bible.
15 Gamerscore
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Everything Is Terrible
Kill Mom's Heart 5 times.
15 Gamerscore
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A Fetus in a Jar
Kill Mom's Heart 9 times.
15 Gamerscore
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Blue Baby
Kill Mom's Heart 10 times.
15 Gamerscore
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It Lives
Kill Mom's Heart 11 times.
15 Gamerscore
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Forget Me Now
Kill Satan with ???.
15 Gamerscore
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The Book of Sin
Kill all 7 sins.
15 Gamerscore
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The Polaroid
Beat Cathedral 5 times.
20 Gamerscore
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The Negative
Beat Sheol 5 times.
20 Gamerscore
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Golden God
You are the best!
30 Gamerscore
-
Platinum God
Collect all items and unlock all secrets and endings.
40 Gamerscore
-
Real Platinum God
100% the game!
50 Gamerscore
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Lilith
Beat Greed Mode with Azazel
15 Gamerscore
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Cambion Conception
Kill ??? with Lilith
15 Gamerscore
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Succubus
Kill The Lamb with Lilith
15 Gamerscore
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Keeper
Donate 1000 coins in Greed Mode
30 Gamerscore
-
Deep Pockets
Kill ??? with Keeper
15 Gamerscore
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Karma
Kill The Lamb with Keeper
15 Gamerscore
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1001%
Collect all items and unlock all secrets
50 Gamerscore
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New Area
Unlocked a new area
15 Gamerscore
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Delirious
Beat Delirium
30 Gamerscore
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1000000%
Just Stop!
50 Gamerscore
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Apollyon
Kill Mega Satan
30 Gamerscore
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Greedier!
Donate 500 coins to the Greed Machine
15 Gamerscore
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The Gate is Open!
Kill The Lamb
15 Gamerscore
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The Forgotten
Uncover some lost remains..
30 Gamerscore
-
A Secret Exit
Complete ??? 3 times.
15 Gamerscore
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Bethany
Beat Hard mode as Lazarus without losing a life
15 Gamerscore
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Jacob & Esau
You are just like your father...
15 Gamerscore
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Red Key
The other side is calling...
15 Gamerscore
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Mega Mush
Beat everything in Hard Mode as every character.
30 Gamerscore
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Death Certificate
...
30 Gamerscore
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Dead God
RIP
60 Gamerscore